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Painkiller Jane

2007 ★ 6.0 1 season 22 eps TV-MA

Sci-Fi & Fantasy

Action & Adventure

Painkiller Jane is an American-Canadian science fiction and action television series based on the comic book character of the same name. Airing on the Sci Fi Channel in the US starting April 13, 2007 and Global in Canada, it starred Kristanna Loken as the titular character. On August 15, 2007, it was canceled after one season of 22 episodes.

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Where to watch Painkiller Jane

Painkiller Jane is available to stream on Nabby via 6 verified sources, aggregated from publicly available embed providers. The sci-fi & fantasy from Gil Grant has 1 season and 22 total episodes, rated 6.0/10 by 55 viewers.

Last verified: October 19, 2026 · Source: TMDB

Episodes 22 total across 1 season

22 episodes20073 watched

Jane Vasco with the help of a new covert government unit must track down and contain the spread of "Neuros," genetically altered humans with extraordinary powers.

Toy Soldiers✓

When military stockpiles start to go missing before a presidential visit, Jane and the team are forced into high alert. Meanwhile, Jane confronts a Neuro with the ability to control the dead.

Piece of Mind✓

A Neuro with the ability to steal memory and knowledge preys on Riley putting the security of the entire operation in jeopardy.

Catch Me if You Can✓

A Neuro who can see the future warns Jane and the team of their impending death on the day they arrest him. Meanwhile, the team is disturbed by the psychic's purchases

Nothing To Fear But Fear Itself✓

When inhabitants of an FBI safe house start to experience unexplained dreams and visions, Jane and crew must investigate potential Neuro activity.

While investigating psychiatric patients who share the same unusual nightmare, Jane and Maureen suspect a Neuro has the ability to use nightmares as weapons.

Higher Court✓

The team investigate the suicides of individuals placed in witness protection and discover a Neuro who is capable of creating hallucinations.

Friendly Fire✓

Awakening in a hospital Jane learns that she murdered Riley. Meanwhile, Maureen investigates a doctor researching Neuros.

Trial by Fire✓

Connor is arrested for arson and murder while out hunting for a Neuro, which is believed to have started numerous house fires.

Portraits of Lauren Gray✓

A young woman suddenly ages overnight, Jane and Maureen go undercover to find the cause.

Ghost in the Machine✓

Connor suffers a series of unfortunate events, believing it to be coincidental. However, he learns that members of his former police squad have died of strange causes.

Something Nasty in the Neighborhood✓

Jane and Connor go undercover in a small town, posed as a married couple, after a federal agent's disappearance prompts an investigation.

An investigation is started after Neuros begin to die before the team can apprehend them.

The Amazing Howie✓

Howie is a magician who can miraculously perform the impossible, which prompts Riley to begin an investigation into possible Neuro activity.

Sabotage hinders Jane's efforts to catch a Neuro, she becomes suspicious of a faith healer that she has been visiting.

Thanks For the Memories✓

Jane seeks help from a Neuro after Brian (Jane's boyfriend) and Joe forget who she is, the Neuro has the ability to remove and store memories within his mind.

A Neuro causes the team to become stuck in a timeloop, causing them to relive the same day repeatedly. Meanwhile, the Neuro who caused the timeloop tries to finish an assassination.

Jane discovers the disturbing truth about her abilities while searching for a Neuro who escaped the team.

What Lies Beneath✓

The team respond when several incarcerated Neuros revolt and launch a prison break.

The Beast of Bolnar✓

The residents of a small village are plagued by an invisible presence which is attacking and murdering the villagers.

Sep 14, 2007★ 5.0

Andre encounters a Neuro from his past that was chipped, but he learns that she has regained her abilities and she has a grudge.

Several dangerous Neuros launch a prison break after an emergency at NICO.

Frequently asked

How many seasons does Painkiller Jane have?

Painkiller Jane has 1 season with 22 episodes in total.

Is Painkiller Jane still on the air?

Painkiller Jane has ended and is no longer in production.

What network airs Painkiller Jane?

Painkiller Jane airs on Syfy, Global TV.

When did Painkiller Jane first air?

Painkiller Jane first aired on April 13, 2007.

Cast

Kristanna Loken

Kristanna Loken

Jane Vasco

Rob Stewart

Rob Stewart

Andre McBride

Noah Dalton Danby

Noah Dalton Danby

Connor King

Stephen Lobo

Stephen Lobo

Seth Carpenter

Sean Owen Roberts

Sean Owen Roberts

Riley Jensen

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